Panoply™ Human UGT1A4 Knockdown Stable Cell Line

Name: Panoply™ Human UGT1A4 Knockdown Stable Cell Line
SKU: CSC-DC017049
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC017049

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC017049
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	UGT1A4
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	UGT1A4 UDP glucuronosyltransferase 1 family, polypeptide A4 [ Homo sapiens ]
Gene Symbol	UGT1A4
Synonyms	UGT1A4; UDP glucuronosyltransferase 1 family, polypeptide A4; UDP glycosyltransferase 1 family, polypeptide A4; UDP-glucuronosyltransferase 1-4; HUG BR2; UGT1D; UDP-glucuronosyltransferase 1-D; UDP-glucuronosyltransferase 1A4; bilirubin-specific UDPGT isozyme 2; bilirubin UDP-glucuronosyltransferase isozyme 2; UDPGT; UGT-1D; UGT1.4; HUG-BR2; UGT1-04; UDPGT 1-4;
Gene ID	54657
Uni Prot ID	P22310
m RNA Refseq	BC139784
Chromosome Location	2q37
Function	enzyme binding; glucuronosyltransferase activity; protein heterodimerization activity; protein homodimerization activity; NOT retinoic acid binding;
Pathway	Arylamine metabolism, organism-specific biosystem; Ascorbate and aldarate metabolism, organism-specific biosystem; Ascorbate and aldarate metabolism, conserved biosystem; Ascorbate biosynthesis, animals, glucose-1P => ascorbate, organism-specific biosystem; Ascorbate biosynthesis, animals, glucose-1P => ascorbate, conserved biosystem;
MIM	606429

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