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UGT1A4


Official Full Name
UDP glucuronosyltransferase family 1 member A4
Organism
Homo sapiens
Gene ID
54657
Background
This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. This enzyme has some glucuronidase activity towards bilirubin, although is is more active on amines, steroids, and sapogenins. [provided by RefSeq, Jul 2008]
Synonyms
GNT1; UGT1; UDPGT; UGT1A; UGT1D; UGT-1A; UGT-1D; UGT1.1; UGT1.4; UGT1A1; HUG-BR2; UGT1-01; UGT1-04; UGT1A4S; hUG-BR1; UDPGT 1-4

Cat.No. Product Name Price
SHH440080 shRNA set against Human UGT1A4 (NM_007120.2) Inquiry
SHW013610 shRNA set against Danio rerio UGT1A4 (NM_001177344) Inquiry
Cat.No. Product Name Price
CDCL186680 Human UGT1A4 ORF clone(NM_007120.2) Inquiry
CDFH020825 Human UGT1A4 cDNA Clone(NM_007120.2) Inquiry
MiUTR1H-10991 UGT1A4 miRNA 3'UTR clone Inquiry
CDCB175085 Danio rerio UGT1A4 ORF Clone (NM_001177344) Inquiry
CDCB180677 Rabbit UGT1-4 ORF clone (NM_001089322.1) Inquiry
CDCS413078 Human UGT1A4 ORF Clone (BC139784) Inquiry
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