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Panoply™ Human TSC1 Knockdown Stable Cell Line

Cat.No.
CSC-DC016699
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
TSC1
Synonyms
TSC1; tuberous sclerosis 1; TSC; hamartin; KIAA0243; LAM; tumor suppressor; tuberous sclerosis 1 protein; MGC86987;
Gene ID
UniProt ID
Q92574
mRNA Refseq
BC047772
Chromosome Location
9q34
Function
GTPase activating protein binding; GTPase regulator activity; chaperone binding; protein N-terminus binding; protein binding;
Pathway
Energy dependent regulation of mTOR by LKB1-AMPK, organism-specific biosystem; IRS-mediated signalling, organism-specific biosystem; IRS-related events, organism-specific biosystem; Inhibition of TSC complex formation by PKB, organism-specific biosystem; Insulin Signaling, organism-specific biosystem; Insulin receptor signalling cascade, organism-specific biosystem; Insulin signaling pathway, organism-specific biosystem;
MIM

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