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Panoply™ Human TOP2A Knockdown Stable Cell Line

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Cat.No.
CSC-DC016434
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Gene
TOP2A
Gene Species
Human
Host Cell
HEK293 (Hela and other cell types are also available)
Growth Properties
Adherent
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Size
2 × 10^6 cells / vial
Storage
Liquid Nitrogen
Ship
Dry Ice
Gene Information
Official Symbol
TOP2A
Synonyms
TOP2; TP2A
GeneID
mRNA Refseq
Protein Refseq
MIM
UniProt ID
P11388
Chromosome Location
17q21-q22
Pathway
Cell Cycle, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem; G0 and Early G1, organism-specific biosystem; Integrated Pancreatic Cancer Pathway, organism-specific biosystem; Mitotic G1-G1/S phases, organism-specific biosystem;
Function
ATP binding; DNA binding; DNA topoisomerase (ATP-hydrolyzing) activity; DNA-dependent ATPase activity; chromatin binding; drug binding; enzyme binding; histone deacetylase binding; protein C-terminus binding; protein binding; protein heterodimerization activity; protein homodimerization activity; protein kinase C binding; sequence-specific DNA binding; structure-specific DNA binding; ubiquitin binding;

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