Panoply™ Human TLE4 Knockdown Stable Cell Line

Name: Panoply™ Human TLE4 Knockdown Stable Cell Line
SKU: CSC-DC015991
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC015991

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC015991
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	TLE4
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	TLE4 transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) [ Homo sapiens ]
Gene Symbol	TLE4
Synonyms	ESG; BCE1; ESG4; GRG4; BCE-1; E(spI)
Gene Description	transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
Gene ID	7091
Uni Prot ID	O60756
m RNA Refseq	NM_007005.3
Protein Refseq	NP_008936.2
Chromosome Location	9q21.31
Function	molecular_function;
Pathway	Calcineurin-regulated NFAT-dependent transcription in lymphocytes, organism-specific biosystem; NOTCH1 Intracellular Domain Regulates Transcription, organism-specific biosystem; Regulation of Wnt-mediated beta catenin signaling and target gene transcription, organism-specific biosystem; Signal Transduction, organism-specific biosystem; Signaling by NOTCH, organism-specific biosystem; Signaling by NOTCH1, organism-specific biosystem;
MIM	605132

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