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TIRAP


Official Full Name
TIR domain containing adaptor protein
Organism
Homo sapiens
Gene ID
114609
Background
The innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs), which identify pathogen-associated molecular patterns. Different TLRs recognize different pathogen-associated molecular patterns and all TLRs have a Toll-interleukin 1 receptor (TIR) domain, which is responsible for signal transduction. The protein encoded by this gene is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system. It activates NF-kappa-B, MAPK1, MAPK3 and JNK, which then results in cytokine secretion and the inflammatory response. Alternative splicing of this gene results in several transcript variants; however, not all variants have been fully described. [provided by RefSeq, Jul 2008]
Synonyms
Mal; wyatt; BACTS1; MyD88-2

Cat.No. Product Name Price
SHH427648 shRNA set against Human TIRAP (NM_001039661.1) Inquiry
SHH427652 shRNA set against Mouse TIRAP (NM_054096.2) Inquiry
SHL071934 shRNA set against Human TIRAP(NM_148910.2) Inquiry
SHL071936 shRNA set against Human TIRAP(NM_001039661.1) Inquiry
SHL072054 shRNA set against Human TIRAP(NM_148910.2) Inquiry
SHW001141 shRNA set against Chicken TIRAP (NM_001024829) Inquiry
Cat.No. Product Name Price
CDFH019651 Human TIRAP cDNA Clone(NM_001039661.1) Inquiry
MiUTR1H-10422 TIRAP miRNA 3'UTR clone Inquiry
MiUTR1H-10423 TIRAP miRNA 3'UTR clone Inquiry
CDCB162616 Chicken TIRAP ORF Clone (NM_001024829) Inquiry
CDCB194394 Rabbit TIRAP ORF clone (XM_008259401.1) Inquiry
CDCH091228 human TIRAP ORF clone (NM_148910.2) Inquiry
CDCR242823 Mouse Tirap ORF Clone(NM_001177845.1) Inquiry
CDCR242825 Mouse Tirap ORF Clone(NM_001177846.1) Inquiry
CDCR242827 Mouse Tirap ORF Clone(NM_001177847.1) Inquiry
CDCR264707 Mouse Tirap ORF Clone(NM_054096.2) Inquiry
CDCR343817 Human TIRAP ORF Clone(NM_001039661.1) Inquiry
CDCS406975 Human TIRAP ORF Clone (BC032474) Inquiry
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