Panoply™ Human TIMP2 Over-expressing Stable Cell Line

Name: Panoply™ Human TIMP2 Over-expressing Stable Cell Line
SKU: CSC-SC015970
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-SC015970

Host Cell : HEK293 (CHO and other cell types are also available) Size : >1x10⁶ frozen cells/vial

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Cell Line Information

Cell Culture Information

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Gene Information

Cat. No.	CSC-SC015970
Description	Using Creative Biogene's proprietary lentiviral vectors, we subclone the target gene into lentivector, generate the lentivirus particles, sequentially infect the cell line HEK293 (other cell types are also available according to your requirements), and select the clones constantly expressing target gene at high level.
Target Gene	TIMP2
Gene Species	Homo sapiens (Human)
Host Cell	HEK293 (CHO and other cell types are also available)
Host Cell Species	Species varies
Applications	1. Gene expression studies 2. Signaling pathway research 3. Drug screening and toxicology 4. Disease research
Size	2 × 10^6 cells / vial
Stability	Validated for at least 10 passages
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid nitrogen
Shipping	Dry Ice

Revival

Rapidly thaw cells in a 37°C water bath. Transfer contents into a tube containing pre-warmed media. Centrifuge cells and seed into a 25 cm2 flask containing pre-warmed media.

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	TIMP2 TIMP metallopeptidase inhibitor 2 [ Homo sapiens ]
Gene Symbol	TIMP2
Synonyms	CSC-21K
Gene Description	TIMP metallopeptidase inhibitor 2
Gene ID	7077
Uni Prot ID	P16035
m RNA Refseq	NM_003255.4
Protein Refseq	NP_003246.1
Chromosome Location	17q25
Function	enzyme activator activity; integrin binding; metal ion binding; metalloendopeptidase inhibitor activity;
Pathway	Activation of Matrix Metalloproteinases, organism-specific biosystem; Angiogenesis, organism-specific biosystem; Degradation of the extracellular matrix, organism-specific biosystem; Extracellular matrix organization, organism-specific biosystem; Matrix Metalloproteinases, organism-specific biosystem;
MIM	188825

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