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Panoply™ Human SMAD7 Knockdown Stable Cell Line

Cat.No.
CSC-DC014717
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
SMAD7
Synonyms
CRCS3; MADH7; MADH8
Gene ID
UniProt ID
O15105
mRNA Refseq
Protein Refseq
Chromosome Location
18q21.1
Function
I-SMAD binding; activin binding; beta-catenin binding; collagen binding; protein binding; sequence-specific DNA binding transcription factor activity; transcription regulatory region DNA binding; transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity; type I transforming growth factor beta receptor binding; ubiquitin protein ligase binding;
Pathway
ALK1 signaling events, organism-specific biosystem; BMP receptor signaling, organism-specific biosystem; Downregulation of TGF-beta receptor signaling, organism-specific biosystem; Endocytosis, organism-specific biosystem; Endocytosis, conserved biosystem; Gene Expression, organism-specific biosystem; Generic Transcription Pathway, organism-specific biosystem;
MIM

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