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SMAD7


Official Full Name
SMAD family member 7
Organism
Homo sapiens
Gene ID
4092
Background
The protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF-beta receptor type-1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
Synonyms
CRCS3; MADH7; MADH8

Cat.No. Product Name Price
SHH413020 shRNA set against Human SMAD7 (NM_005904.3) Inquiry
SHH413024 shRNA set against Mouse SMAD7 (NM_001042660.1) Inquiry
SHH413028 shRNA set against Rat SMAD7 (NM_030858.1) Inquiry
SHL015274 shRNA set against Mouse Smad7(NM_001042660.1) Inquiry
SHL015328 shRNA set against Rat Smad7(NM_030858.1) Inquiry
SHW015452 shRNA set against Danio rerio SMAD7 (NM_175082) Inquiry
Cat.No. Product Name Price
CDCH083354 Mouse Smad7 ORF clone (NM_001042660.1) Inquiry
CDFR012390 Rat Smad7 cDNA Clone(NM_030858.1) Inquiry
MiUTR1M-10976 SMAD7 miRNA 3'UTR clone Inquiry
MiUTR1R-07555 SMAD7 miRNA 3'UTR clone Inquiry
MiUTR3H-05425 SMAD7 miRNA 3'UTR clone Inquiry
CDCB176927 Danio rerio SMAD7 ORF Clone (NM_175082) Inquiry
CDCB180598 Rabbit SMAD7 ORF clone (XM_002713526.2) Inquiry
CDCH083348 human SMAD7 ORF clone (NM_001190823.1) Inquiry
CDCH083350 human SMAD7 ORF clone (NM_001190822.1) Inquiry
CDCH083352 human SMAD7 ORF clone (NM_001190821.1) Inquiry
CDCR379427 Rat Smad7 ORF Clone(NM_030858.1) Inquiry
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