Panoply™ Human SETDB2 Knockdown Stable Cell Line

Name: Panoply™ Human SETDB2 Knockdown Stable Cell Line
SKU: CSC-DC014088
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC014088

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC014088
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	SETDB2
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	SETDB2 SET domain, bifurcated 2 [ Homo sapiens ]
Gene Symbol	SETDB2
Synonyms	SETDB2; SET domain, bifurcated 2; C13orf4, chromosome 13 open reading frame 4; histone-lysine N-methyltransferase SETDB2; CLLD8; CLLL8; KMT1F; lysine N-methyltransferase 1F; chronic lymphocytic leukemia deletion region 8; chronic lymphocytic leukemia deletion region gene 8 protein; C13orf4; DKFZp586I0123; DKFZp761J1217;
Gene ID	83852
Uni Prot ID	Q96T68
m RNA Refseq	BC047434
Chromosome Location	13q14
Function	DNA binding; histone methyltransferase activity (H3-K9 specific); metal ion binding; methyltransferase activity; transferase activity; zinc ion binding;
Pathway	Lysine degradation, organism-specific biosystem; Lysine degradation, conserved biosystem;
MIM	607865

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