Panoply™ Human RRM2B Knockdown Stable Cell Line

Name: Panoply™ Human RRM2B Knockdown Stable Cell Line
SKU: CSC-DC013628
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC013628

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC013628
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	RRM2B
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	RRM2B ribonucleotide reductase M2 B (TP53 inducible) [ Homo sapiens ]
Gene Symbol	RRM2B
Synonyms	RRM2B; ribonucleotide reductase M2 B (TP53 inducible); ribonucleoside-diphosphate reductase subunit M2 B; p53R2; TP53-inducible ribonucleotide reductase M2 B; p53-inducible ribonucleotide reductase small subunit 2 homolog; p53-inducible ribonucleotide reductase small subunit 2-like protein; p53-inducible ribonucleotide reductase small subunit 2 short form beta; P53R2; MTDPS8A; MTDPS8B; MGC42116; MGC102856; DKFZp686M05248;
GeneID	50484
Uni ProtID	Q7LG56
mRNA Refseq	BC117496
Chromosome Location	8q23.1
Function	oxidoreductase activity; ribonucleoside-diphosphate reductase activity; transition metal ion binding;
Pathway	Direct p53 effectors, organism-specific biosystem; Glutathione metabolism, organism-specific biosystem; Glutathione metabolism, conserved biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of nucleotides, organism-specific biosystem; Nucleotide Metabolism, organism-specific biosystem;
MIM	604712

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