Panoply™ Human RET Knockdown Stable Cell Line

Name: Panoply™ Human RET Knockdown Stable Cell Line
SKU: CSC-DC013175
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC013175

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

Safety and Packaging

Gene Information

Cat. No.	CSC-DC013175
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	RET
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	RET ret proto-oncogene [ Homo sapiens ]
Gene Symbol	RET
Synonyms	PTC; MTC1; HSCR1; MEN2A; MEN2B; RET51; CDHF12; CDHR16; RET-ELE1
Gene Description	ret proto-oncogene
GeneID	5979
Uni ProtID	P07949
mRNA Refseq	NM_020975.4
Protein Refseq	NP_066124.1
Chromosome Location	10q11.2
Pathway	Endocytosis, organism-specific biosystem; Endocytosis, conserved biosystem; Pathways in cancer, organism-specific biosystem; SIDS Susceptibility Pathways, organism-specific biosystem; Signaling events regulated by Ret tyrosine kinase, organism-specific biosystem; Thyroid cancer, organism-specific biosystem; Thyroid cancer, conserved biosystem;
MIM	164761

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