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Panoply™ Human PSEN2 Knockdown Stable Cell Line

Cat.No.
CSC-DC012561
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
PSEN2
Synonyms
AD4; PS2; AD3L; STM2; CMD1V
Gene Description
presenilin 2 (Alzheimer disease 4)
Gene ID
UniProt ID
P49810
mRNA Refseq
Protein Refseq
Chromosome Location
1q31-q42
Function
aspartic-type endopeptidase activity; endopeptidase activity; protein binding;
Pathway
Activated NOTCH1 Transmits Signal to the Nucleus, organism-specific biosystem; Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem; Alzheimers Disease, organism-specific biosystem; Cell death signalling via NRAGE, NRIF and NADE, organism-specific biosystem; Delta-Notch Signaling Pathway, organism-specific biosystem; LKB1 signaling events, organism-specific biosystem;
MIM

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