Panoply™ Human PLCG1 Knockdown Stable Cell Line

Name: Panoply™ Human PLCG1 Knockdown Stable Cell Line
SKU: CSC-DC011902
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC011902

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC011902
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	PLCG1
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	PLCG1 phospholipase C, gamma 1 [ Homo sapiens ]
Gene Symbol	PLCG1
Synonyms	PLC1; NCKAP3; PLC-II; PLC148; PLCgamma1
Gene Description	phospholipase C, gamma 1
Gene ID	5335
Uni Prot ID	A2A284
m RNA Refseq	NM_002660.2
Protein Refseq	NP_002651.2
Chromosome Location	20q12-q13.1
Function	calcium ion binding; glutamate receptor binding; insulin receptor binding; neurotrophin TRKA receptor binding; phosphatidylinositol phospholipase C activity; phosphatidylinositol phospholipase C activity; phospholipase C activity; phospholipid binding; phosphoprotein binding; protein binding; receptor signaling protein activity; receptor tyrosine kinase binding;
Pathway	Adaptive Immune System, organism-specific biosystem; Angiogenesis, organism-specific biosystem; Antigen Activates B Cell Receptor Leading to Generation of Second Messengers, organism-specific biosystem; Antiviral mechanism by IFN-stimulated genes, organism-specific biosystem; Axon guidance, organism-specific biosystem; B Cell Receptor Signaling Pathway, organism-specific biosystem; Calcium signaling pathway, organism-specific biosystem;
MIM	172420

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