Panoply™ Human NUMB Knockdown Stable Cell Line

Name: Panoply™ Human NUMB Knockdown Stable Cell Line
SKU: CSC-DC010728
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC010728

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

Safety and Packaging

Gene Information

Cat. No.	CSC-DC010728
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	NUMB
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	NUMB numb homolog (Drosophila) [ Homo sapiens ]
Gene Symbol	NUMB
Synonyms	S171; C14orf41; c14_5527
Gene Description	numb homolog (Drosophila)
Gene ID	8650
Uni Prot ID	P49757
m RNA Refseq	NM_003744.5
Protein Refseq	NP_003735.3
Chromosome Location	14q24.3
Function	alpha-catenin binding; beta-catenin binding; cadherin binding;
Pathway	Activated NOTCH1 Transmits Signal to the Nucleus, organism-specific biosystem; Axon guidance, organism-specific biosystem; Delta-Notch Signaling Pathway, organism-specific biosystem; Developmental Biology, organism-specific biosystem; L1CAM interactions, organism-specific biosystem; Notch Signaling Pathway, organism-specific biosystem; Notch signaling pathway, organism-specific biosystem;
MIM	603728

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