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NUMB

Official Full Name
NUMB endocytic adaptor protein
Organism
Homo sapiens
GeneID
8650
Background
The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
Synonyms
S171; C14orf41; c14_5527;

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