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Panoply™ Human NEIL3 Knockdown Stable Cell Line

For research use only. Not intended for any clinical use.

Cat. No. :   CSC-DC010285

Host Cell :   HEK293 (Hela and other cell types are also available) Validation :   Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No. CSC-DC010285
Description Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene NEIL3
Host Cell HEK293 (Hela and other cell types are also available)
Host Cell Species Homo sapiens (Human)
Applications

(1) Studying gene functions

(2) Studying gene interactions and signaling pathways

(3) Target validation and drug discovery

(4) Designing diseases models

Size >1 × 106 cells / vial
Stability Validated for at least 10 passages
Validation Real-Time RCR
Quality Control Negative for bacteria, yeast, fungi and mycoplasma.
Storage Liquid Nitrogen
Shipping Dry Ice
Mycoplasma Negative
Format One frozen vial containing millions of cells
Storage Liquid nitrogen
Safety Considerations The following safety precautions should be observed.
1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum.
2. No eating, drinking or smoking while handling the stable line.
3. Wash hands after handling the stable line and before leaving the lab.
4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells.
5. All waste should be considered hazardous.
6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship Dry ice
Gene Name NEIL3 nei endonuclease VIII-like 3 (E. coli) [ Homo sapiens ]
Gene Symbol NEIL3
Synonyms FGP2; FPG2; NEI3; hFPG2; hNEI3
Gene ID 55247
Uni Prot ID Q8TAT5
m RNA Refseq NM_018248.2
Protein Refseq NP_060718.2
Chromosome Location 4q34.3
Function NOT DNA N-glycosylase activity; DNA N-glycosylase activity; DNA-(apurinic or apyrimidinic site) lyase activity; bubble DNA binding; damaged DNA binding; double-stranded DNA binding; single-stranded DNA binding; zinc ion binding;
Pathway Base excision repair, organism-specific biosystem; Base excision repair, conserved biosystem;
MIM 608934
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