Human NEIL3 Knockdown Cell Line - Glioma

Name: Human NEIL3 Knockdown Cell Line - Glioma
SKU: CSC-RK0217
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-RK0217

Host Cell : Glioma Validation : Real-Time RCR

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Cell Line Information

Safety and Packaging

Gene Information

Cat. No.	CSC-RK0217
Description	This cell line is engineered to stably express shRNA targeting human NEIL3.
Target Gene	NEIL3
Host Cell	Glioma
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Storage	Liquid nitrogen
Shipping	Dry ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	NEIL3 nei endonuclease VIII-like 3 (E. coli) [ Homo sapiens ]
Gene Symbol	NEIL3
Synonyms	FGP2; FPG2; NEI3; hFPG2; hNEI3
Gene ID	55247
Uni Prot ID	Q8TAT5
m RNA Refseq	NM_018248.2
Protein Refseq	NP_060718.2
Chromosome Location	4q34.3
Function	NOT DNA N-glycosylase activity; DNA N-glycosylase activity; DNA-(apurinic or apyrimidinic site) lyase activity; bubble DNA binding; damaged DNA binding; double-stranded DNA binding; single-stranded DNA binding; zinc ion binding;
Pathway	Base excision repair, organism-specific biosystem; Base excision repair, conserved biosystem;
MIM	608934

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