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Human NEIL3 Knockdown Cell Line-LN428 Glioma

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Cat.No.
CSC-RK0217
Background
NEIL3 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction.
Growth Properties
Adherent
Morphology
Epithelial
Host Cell
LN428 glioma
Ship
Dry ice
Gene Information
Official Symbol
NEIL3
Synonyms
NEIL3; nei endonuclease VIII-like 3 (E. coli); endonuclease 8-like 3; FLJ10858; FPG2; hFPG2; hNEI3; nei-like protein 3; DNA glycosylase FPG2; DNA glycosylase hFPG2; endonuclease VIII-like 3; DNA glycosylase/AP lyase Neil3; FGP2; NEI3;
Gene ID
MIM
UniProt ID
Q8TAT5
Chromosome Location
4q34
Pathway
Base excision repair, organism-specific biosystem; Base excision repair, conserved biosystem;
Function
NOT DNA N-glycosylase activity; DNA N-glycosylase activity; DNA-(apurinic or apyrimidinic site) lyase activity; bubble DNA binding; damaged DNA binding; double-stranded DNA binding; lyase activity; metal ion binding; single-stranded DNA binding; zinc ion binding;

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