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Panoply™ Human MSH6 Knockdown Stable Cell Line

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Cat.No.
CSC-DC009823
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Gene
MSH6
Gene Species
Human
Host Cell
HEK293 (Hela and other cell types are also available)
Growth Properties
Adherent
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Size
2 × 10^6 cells / vial
Storage
Liquid Nitrogen
Ship
Dry Ice
Gene Information
Official Symbol
MSH6
Synonyms
GTBP; HSAP; HNPCC5
GeneID
mRNA Refseq
Protein Refseq
MIM
UniProt ID
P52701
Chromosome Location
2p16
Pathway
BRCA1-associated genome surveillance complex (BASC), organism-specific biosystem; Colorectal cancer, organism-specific biosystem; Colorectal cancer, conserved biosystem; Integrated Breast Cancer Pathway, organism-specific biosystem; Integrated Cancer pathway, organism-specific biosystem; Mismatch repair, organism-specific biosystem; Mismatch repair, organism-specific biosystem;
Function
contributes_to ADP binding; contributes_to ATP binding; contributes_to ATPase activity; DNA-dependent ATPase activity; contributes_to MutLalpha complex binding; chromatin binding; contributes_to double-stranded DNA binding; contributes_to four-way junction DNA binding; contributes_to guanine/thymine mispair binding; contributes_to magnesium ion binding; contributes_to mismatched DNA binding; contributes_to oxidized purine DNA binding; protein binding; contributes_to protein binding; NOT protein homodimerization activity; contributes_to single guanine insertion binding; contributes_to single thymine insertion binding;

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