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Panoply™ Human MDC1 Knockdown Stable Cell Line

Cat.No.
CSC-DC009332
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
MDC1
Synonyms
NFBD1
Gene Description
mediator of DNA damage checkpoint 1
Gene ID
UniProt ID
A1Z5I9
mRNA Refseq
Protein Refseq
Chromosome Location
6p21.3
Function
FHA domain binding; protein C-terminus binding; protein binding;
Pathway
ATM mediated phosphorylation of repair proteins, organism-specific biosystem; ATM mediated response to DNA double-strand break, organism-specific biosystem; DNA Repair, organism-specific biosystem; Double-Strand Break Repair, organism-specific biosystem; Homologous Recombination Repair, organism-specific biosystem; Homologous recombination repair of replication-independent double-strand breaks, organism-specific biosystem; Recruitment of repair and signaling proteins to double-strand breaks, organism-specific biosystem;
MIM

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