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Panoply™ Human MAP3K1 Knockdown Stable Cell Line

Cat.No.
CSC-DC009165
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
MAP3K1
Synonyms
MEKK; MEKK1; SRXY6; MEKK 1; MAPKKK1
Gene Description
mitogen-activated protein kinase kinase kinase 1
Gene ID
UniProt ID
Q13233
mRNA Refseq
Protein Refseq
Chromosome Location
5q11.2
Function
ATP binding; JUN kinase binding; JUN kinase kinase activity; JUN kinase kinase kinase activity; MAP kinase kinase kinase activity; identical protein binding; mitogen-activated protein kinase binding; mitogen-activated protein kinase kinase binding; protein binding; protein kinase activity; protein kinase activity; protein kinase binding; sphingolipid binding; ubiquitin-protein ligase activity; zinc ion binding;
Pathway
Activated TLR4 signalling, organism-specific biosystem; Apoptosis, organism-specific biosystem; Apoptosis Modulation by HSP70, organism-specific biosystem; BCR signaling pathway, organism-specific biosystem; CD40/CD40L signaling, organism-specific biosystem; CDC42 signaling events, organism-specific biosystem; Caspase cascade in apoptosis, organism-specific biosystem;
MIM

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