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Panoply™ Human MADD Knockdown Stable Cell Line

Cat.No.
CSC-DC009067
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
MADD
Synonyms
MADD; MAP-kinase activating death domain; MAP kinase-activating death domain protein; DENN; KIAA0358; RAB3GEP; Rab3 GDP/GTP exchange factor; insulinoma glucagonoma clone 20; differentially expressed in normal and neoplastic cells; IG20; FLJ35600; FLJ36300;
Gene ID
UniProt ID
Q8WXG6
mRNA Refseq
BC040484
Chromosome Location
11p11.2
Function
Rab guanyl-nucleotide exchange factor activity; death receptor binding; guanyl-nucleotide exchange factor activity; protein binding; protein kinase activator activity;
Pathway
Caspase cascade in apoptosis, organism-specific biosystem; Ceramide signaling pathway, organism-specific biosystem; TNF receptor signaling pathway, organism-specific biosystem;
MIM

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