Panoply™ Human LRP5 Knockdown Stable Cell Line

Name: Panoply™ Human LRP5 Knockdown Stable Cell Line
SKU: CSC-DC008861
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC008861

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC008861
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	LRP5
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	LRP5 low density lipoprotein receptor-related protein 5 [ Homo sapiens ]
Gene Symbol	LRP5
Synonyms	HBM; LR3; OPS; EVR1; EVR4; LRP7; OPPG; BMND1; OPTA1; VBCH2
Gene ID	4041
Uni Prot ID	O75197
m RNA Refseq	NM_002335.2
Protein Refseq	NP_002326.2
Chromosome Location	11q13.4
Function	Wnt-activated receptor activity; Wnt-protein binding; coreceptor activity; protein binding; NOT toxin transporter activity;
Pathway	MicroRNAs in cardiomyocyte hypertrophy, organism-specific biosystem; N-cadherin signaling events, organism-specific biosystem; Wnt Signaling Pathway NetPath, organism-specific biosystem; Wnt Signaling Pathway and Pluripotency, organism-specific biosystem; Wnt signaling network, organism-specific biosystem; Wnt signaling pathway, organism-specific biosystem; Wnt signaling pathway, conserved biosystem;
MIM	603506

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