Panoply™ Human LONP1 Knockdown Stable Cell Line

Name: Panoply™ Human LONP1 Knockdown Stable Cell Line
SKU: CSC-DC008793
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC008793

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC008793
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	LONP1
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	LONP1 lon peptidase 1, mitochondrial [ Homo sapiens ]
Gene Symbol	LONP1
Synonyms	LON; LONP; PIM1; hLON; LonHS; PRSS15
Gene Description	lon peptidase 1, mitochondrial
GeneID	9361
Uni ProtID	P36776
mRNA Refseq	NM_004793.2
Protein Refseq	NP_004784.2
Chromosome Location	19p13.2
Function	ADP binding; ATP binding; ATP-dependent peptidase activity; DNA polymerase binding; G-quadruplex DNA binding; mitochondrial heavy strand promoter anti-sense binding; NOT mitochondrial heavy strand promoter sense binding; mitochondrial light strand promoter anti-sense binding; NOT mitochondrial light strand promoter sense binding; protein binding; sequence-specific DNA binding; serine-type endopeptidase activity; single-stranded DNA binding; single-stranded RNA binding;
MIM	605490

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