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LONP1

Official Full Name
lon peptidase 1, mitochondrial
Background
This gene encodes a mitochondrial matrix protein in the Lon family of ATP-dependent proteases. A similar E. coli protein regulates gene expression by targeting specific regulatory proteins for degradation. This protein binds a specific sequence in the light and heavy chain promoters of the mitochondrial genome which are involved in regulation of DNA replication and transcription.
Synonyms
LONP1; lon peptidase 1, mitochondrial; protease, serine, 15 , PRSS15; lon protease homolog, mitochondrial; hLON; LonHS; PIM1; Serine protease 15; hLON ATP dependent protease; Lon protease like protein; LONP; MGC1498; PRSS15; LON; LON protease; Mitochondrial ATP dependent protease Lon; Mitochondrial lon peptidase 1; Protease serine 15; protease, serine, 15; Lon protease-like protein; hLON ATP-dependent protease; mitochondrial lon protease-like protein; mitochondrial ATP-dependent protease Lon

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