Panoply™ Human IQGAP1 Over-expressing Stable Cell Line

Name: Panoply™ Human IQGAP1 Over-expressing Stable Cell Line
SKU: CSC-SC007725
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-SC007725

Host Cell : HEK293 (CHO and other cell types are also available) Size : >1x10⁶ frozen cells/vial

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Cell Line Information

Cell Culture Information

Safety and Packaging

Gene Information

Cat. No.	CSC-SC007725
Description	Using Creative Biogene's proprietary lentiviral vectors, we subclone the target gene into lentivector, generate the lentivirus particles, sequentially infect the cell line HEK293 (other cell types are also available according to your requirements), and select the clones constantly expressing target gene at high level.
Target Gene	IQGAP1
Gene Species	Homo sapiens (Human)
Host Cell	HEK293 (CHO and other cell types are also available)
Host Cell Species	Species varies
Applications	1. Gene expression studies 2. Signaling pathway research 3. Drug screening and toxicology 4. Disease research
Size	2 × 10^6 cells / vial
Stability	Validated for at least 10 passages
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid nitrogen
Shipping	Dry Ice

Revival

Rapidly thaw cells in a 37°C water bath. Transfer contents into a tube containing pre-warmed media. Centrifuge cells and seed into a 25 cm2 flask containing pre-warmed media.

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	IQGAP1 IQ motif containing GTPase activating protein 1 [ Homo sapiens ]
Gene Symbol	IQGAP1
Synonyms	IQGAP1; IQ motif containing GTPase activating protein 1; ras GTPase-activating-like protein IQGAP1; HUMORFA01; KIAA0051; p195; RasGAP like with IQ motifs; SAR1; RasGAP-like with IQ motifs;
GeneID	8826
Uni ProtID	P46940
mRNA Refseq	BC139731
Chromosome Location	15q26.1
Function	GTPase activator activity; GTPase inhibitor activity; Rac GTPase binding; Ras GTPase activator activity; calmodulin binding; protein binding; protein phosphatase binding;
Pathway	Adherens junction, organism-specific biosystem; Adherens junction, conserved biosystem; C-MYB transcription factor network, organism-specific biosystem; CDC42 signaling events, organism-specific biosystem; Cell-Cell communication, organism-specific biosystem; E-cadherin signaling in the nascent adherens junction, organism-specific biosystem; ErbB1 downstream signaling, organism-specific biosystem;
MIM	603379

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