Panoply™ Human IKZF1 Knockdown Stable Cell Line

Name: Panoply™ Human IKZF1 Knockdown Stable Cell Line
SKU: CSC-DC007523
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC007523

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC007523
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	IKZF1
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	IKZF1 IKAROS family zinc finger 1 (Ikaros) [ Homo sapiens ]
Gene Symbol	IKZF1
Synonyms	IKZF1; IKAROS family zinc finger 1 (Ikaros); zinc finger protein, subfamily 1A, 1 (Ikaros) , ZNFN1A1; DNA-binding protein Ikaros; hIk 1; Hs.54452; IKAROS; LyF 1; CLL-associated antigen KW-6; Ikaros (zinc finger protein); ikaros family zinc finger protein 1; lymphoid transcription factor LyF-1; zinc finger protein, subfamily 1A, 1 (Ikaros); IK1; LYF1; hIk-1; PRO0758; ZNFN1A1;
Gene ID	10320
Uni Prot ID	Q13422
m RNA Refseq	BC018349
Chromosome Location	7pter-7qter
Function	DNA binding; metal ion binding; nucleic acid binding; protein heterodimerization activity; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; zinc ion binding;
Pathway	Calcineurin-regulated NFAT-dependent transcription in lymphocytes, organism-specific biosystem;
MIM	603023

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