Panoply™ Human GNB3 Knockdown Stable Cell Line

Name: Panoply™ Human GNB3 Knockdown Stable Cell Line
SKU: CSC-DC006398
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC006398

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC006398
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	GNB3
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3 [ Homo sapiens ]
Gene Symbol	GNB3
Gene Description	guanine nucleotide binding protein (G protein), beta polypeptide 3
Gene ID	2784
Uni Prot ID	F1T0G5
m RNA Refseq	NM_002075.2
Protein Refseq	NP_002066.1
Chromosome Location	12p13
Function	GTPase activity; GTPase binding; signal transducer activity;
Pathway	ADP signalling through P2Y purinoceptor 1, organism-specific biosystem; ADP signalling through P2Y purinoceptor 12, organism-specific biosystem; Activation of G protein gated Potassium channels, organism-specific biosystem; Activation of GABAB receptors, organism-specific biosystem; Activation of Kainate Receptors upon glutamate binding, organism-specific biosystem; Alcoholism, organism-specific biosystem; Alcoholism, conserved biosystem;
MIM	139130

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