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Panoply™ Human FER Knockdown Stable Cell Line

For research use only. Not intended for any clinical use.

Cat. No. :   CSC-DC005670

Host Cell :   HEK293 (Hela and other cell types are also available) Validation :   Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No. CSC-DC005670
Description Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene FER
Host Cell HEK293 (Hela and other cell types are also available)
Host Cell Species Homo sapiens (Human)
Applications

(1) Studying gene functions

(2) Studying gene interactions and signaling pathways

(3) Target validation and drug discovery

(4) Designing diseases models

Size >1 × 106 cells / vial
Stability Validated for at least 10 passages
Validation Real-Time RCR
Quality Control Negative for bacteria, yeast, fungi and mycoplasma.
Storage Liquid Nitrogen
Shipping Dry Ice
Mycoplasma Negative
Format One frozen vial containing millions of cells
Storage Liquid nitrogen
Safety Considerations The following safety precautions should be observed.
1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum.
2. No eating, drinking or smoking while handling the stable line.
3. Wash hands after handling the stable line and before leaving the lab.
4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells.
5. All waste should be considered hazardous.
6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship Dry ice
Gene Name FER fer (fps/fes related) tyrosine kinase [ Homo sapiens ]
Gene Symbol FER
Synonyms FerT; TYK3; PPP1R74
Gene Description fer (fps/fes related) tyrosine kinase (phosphoprotein NCP94)
GeneID 2241
Uni ProtID P16591
mRNA Refseq NM_005246.2
Protein Refseq NP_005237.2
Chromosome Location 5q21
Function ATP binding; Rab GTPase binding; actin binding; cadherin binding; epidermal growth factor receptor binding; gamma-catenin binding; lipid binding; non-membrane spanning protein tyrosine kinase activity; protein kinase binding; protein phosphatase 1 binding; protein tyrosine kinase activity;
Pathway Adherens junction, organism-specific biosystem; Adherens junction, conserved biosystem; Fc-epsilon receptor I signaling in mast cells, organism-specific biosystem; Integrated Breast Cancer Pathway, organism-specific biosystem; N-cadherin signaling events, organism-specific biosystem; PDGFR-beta signaling pathway, organism-specific biosystem; Signal Transduction, organism-specific biosystem;
MIM 176942
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