shRNA set against Mouse Fert2 (NM_008000.2)

Name: shRNA set against Mouse Fert2 (NM_008000.2)
SKU: SHH294137
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : SHH294137

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Product Information

Gene Information

Cat. No.	SHH294137
Description	The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr	Fert2
Species	Mouse
Report Gene	GFP
Storage	The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.

Target Gene

Fert2

Background

Enables protein kinase activity and protein phosphatase 1 binding activity. Involved in several processes, including cell surface receptor signaling pathway; cell-cell adhesion mediated by cadherin; and negative regulation of mast cell activation involved in immune response. Acts upstream of with a positive effect on positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction. Acts upstream of or within several processes, including cell adhesion; chemotaxis; and protein autophosphorylation. Predicted to be located in several cellular components, including adherens junction; chromatin; and cytoplasmic side of plasma membrane. Predicted to be part of protein-containing complex. Predicted to be active in plasma membrane. Predicted to colocalize with cell junction; cytoskeleton; and lamellipodium. Is expressed in central nervous system and retina. Orthologous to human FER (FER tyrosine kinase). [provided by Alliance of Genome Resources, Feb 2025]

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