Panoply™ Human ERCC6 Knockdown Stable Cell Line

Name: Panoply™ Human ERCC6 Knockdown Stable Cell Line
SKU: CSC-DC005038
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC005038

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC005038
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	ERCC6
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	ERCC6 excision repair cross-complementing rodent repair deficiency, complementation group 6 [ Homo sapiens ]
Gene Symbol	ERCC6
Synonyms	ERCC6; excision repair cross-complementing rodent repair deficiency, complementation group 6; CKN2; DNA excision repair protein ERCC-6; Cockayne syndrome B protein; CSB; RAD26; Rad26 homolog; ATP-dependent helicase ERCC6; cockayne syndrome protein CSB; Cockayne syndrome group B protein; COFS; ARMD5; COFS1;
GeneID	2074
Uni ProtID	Q03468
mRNA Refseq	BC127104
Chromosome Location	10q11
Function	ATP binding; DNA binding; NOT DNA helicase activity; DNA-dependent ATPase activity; chromatin binding; hydrolase activity; nucleotide binding; protein C-terminus binding; protein N-terminus binding; protein binding; protein complex binding;
Pathway	DNA Repair, organism-specific biosystem; Dual incision reaction in TC-NER, organism-specific biosystem; Formation of transcription-coupled NER (TC-NER) repair complex, organism-specific biosystem; Gene Expression, organism-specific biosystem; Nucleotide Excision Repair, organism-specific biosystem; Nucleotide excision repair, organism-specific biosystem; Nucleotide excision repair, conserved biosystem;
MIM	609413

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