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ERCC6


Official Full Name
ERCC excision repair 6, chromatin remodeling factor
Organism
Homo sapiens
Gene ID
2074
Background
This gene encodes a DNA-binding protein that is important in transcription-coupled excision repair. The encoded protein has ATP-stimulated ATPase activity, interacts with several transcription and excision repair proteins, and may promote complex formation at DNA repair sites. Mutations in this gene are associated with Cockayne syndrome type B and cerebrooculofacioskeletal syndrome 1. Alternative splicing occurs between a splice site from exon 5 of this gene to the 3' splice site upstream of the open reading frame (ORF) of the adjacent gene, piggyback-derived-3 (GeneID:267004), which activates the alternative polyadenylation site downstream of the piggyback-derived-3 ORF. The resulting transcripts encode a fusion protein that shares sequence with the product of each individual gene. [provided by RefSeq, Mar 2016]
Synonyms
CSB; CKN2; COFS; ARMD5; COFS1; POF11; RAD26; UVSS1; CSB-PGBD3

Cat.No. Product Name Price
SHH038333 shRNA set against Mouse Ercc6(NM_001081221.1) Inquiry
SHH286937 shRNA set against Human ERCC6 (NM_000124.2) Inquiry
SHH286941 shRNA set against Mouse ERCC6 (NM_001081221.1) Inquiry
SHH286945 shRNA set against Rat ERCC6 (NM_001107296.1) Inquiry
Cat.No. Product Name Price
CDFR007017 Rat Ercc6 cDNA Clone(NM_001107296.1) Inquiry
MiUTR1M-04461 ERCC6 miRNA 3'UTR clone Inquiry
MiUTR4H-TG03143 ERCC6 miRNA 3'UTR clone Inquiry
SKO0270 ERCC6 Validated sgRNA vector Inquiry
CDCB190317 Rabbit ERCC6 ORF clone (XM_008269831.1) Inquiry
CDCR061110 Mouse Ercc6 ORF clone (NM_001081221.1) Inquiry
CDCR374015 Rat Ercc6 ORF Clone(NM_001107296.1) Inquiry
CDCS405439 Human ERCC6 ORF Clone (BC127104) Inquiry
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