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Panoply™ Human ERCC4 Knockdown Stable Cell Line

Cat.No.
CSC-DC005036
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
ERCC4
Synonyms
XPF; RAD1; ERCC11
Gene Description
excision repair cross-complementing rodent repair deficiency, complementation group 4
Gene ID
UniProt ID
Q92889
mRNA Refseq
Protein Refseq
Chromosome Location
16p13.12
Function
damaged DNA binding; endodeoxyribonuclease activity; contributes_to endodeoxyribonuclease activity; protein C-terminus binding; protein N-terminus binding; protein binding; single-stranded DNA binding; single-stranded DNA specific endodeoxyribonuclease activity; contributes_to structure-specific DNA binding;
Pathway
DNA Repair, organism-specific biosystem; Dual incision reaction in GG-NER, organism-specific biosystem; Dual incision reaction in TC-NER, organism-specific biosystem; Fanconi anemia pathway, organism-specific biosystem; Fanconi anemia pathway, conserved biosystem; Formation of incision complex in GG-NER, organism-specific biosystem; Formation of transcription-coupled NER (TC-NER) repair complex, organism-specific biosystem;
MIM

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