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Panoply™ Human E2F1 Knockdown Stable Cell Line

Cat.No.
CSC-DC004664
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
E2F1
Synonyms
RBP3; E2F-1; RBAP1; RBBP3
Gene Description
E2F transcription factor 1
Gene ID
UniProt ID
Q01094
mRNA Refseq
Protein Refseq
Chromosome Location
20q11.2
Function
DNA binding; DNA binding; core promoter binding; protein binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; sequence-specific DNA binding transcription factor activity; transcription corepressor activity; transcription factor binding;
Pathway
Activation of BH3-only proteins, organism-specific biosystem; Activation of NOXA and translocation to mitochondria, organism-specific biosystem; Activation of PUMA and translocation to mitochondria, organism-specific biosystem; Adipogenesis, organism-specific biosystem; Apoptosis, organism-specific biosystem; Assembly of the pre-replicative complex, organism-specific biosystem; Association of licensing factors with the pre-replicative complex, organism-specific biosystem;
MIM

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