Panoply™ Human CYP2R1 Over-expressing Stable Cell Line

Name: Panoply™ Human CYP2R1 Over-expressing Stable Cell Line
SKU: CSC-SC003964
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-SC003964

Host Cell : HEK293 (CHO and other cell types are also available) Size : >1x10⁶ frozen cells/vial

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Cell Line Information

Cell Culture Information

Safety and Packaging

Gene Information

Cat. No.	CSC-SC003964
Description	Using Creative Biogene's proprietary lentiviral vectors, we subclone the target gene into lentivector, generate the lentivirus particles, sequentially infect the cell line HEK293 (other cell types are also available according to your requirements), and select the clones constantly expressing target gene at high level.
Target Gene	CYP2R1
Gene Species	Homo sapiens (Human)
Host Cell	HEK293 (CHO and other cell types are also available)
Host Cell Species	Species varies
Applications	1. Gene expression studies 2. Signaling pathway research 3. Drug screening and toxicology 4. Disease research
Size	2 × 10^6 cells / vial
Stability	Validated for at least 10 passages
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid nitrogen
Shipping	Dry Ice

Revival

Rapidly thaw cells in a 37°C water bath. Transfer contents into a tube containing pre-warmed media. Centrifuge cells and seed into a 25 cm2 flask containing pre-warmed media.

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1 [ Homo sapiens ]
Gene Symbol	CYP2R1
Gene Description	cytochrome P450, family 2, subfamily R, polypeptide 1
Gene ID	120227
Uni Prot ID	Q6VVX0
m RNA Refseq	NM_024514.4
Protein Refseq	NP_078790.2
Chromosome Location	11p15.2
Function	electron carrier activity; heme binding; iron ion binding; monooxygenase activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; vitamin D3 25-hydroxylase activity;
Pathway	1,25-dihydroxyvitamin D3 biosynthesis, conserved biosystem; Biological oxidations, organism-specific biosystem; Cholecalciferol biosynthesis, organism-specific biosystem; Cholecalciferol biosynthesis, conserved biosystem; Cytochrome P450 - arranged by substrate type, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of lipids and lipoproteins, organism-specific biosystem;
MIM	608713

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