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Panoply™ Human CYP27B1 Knockdown Stable Cell Line

Cat.No.
CSC-DC003950
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
CYP27B1
Synonyms
VDR; CP2B; CYP1; PDDR; VDD1; VDDR; VDDRI; CYP27B; P450c1; CYP1alpha
Gene Description
cytochrome P450, family 27, subfamily B, polypeptide 1
Gene ID
UniProt ID
O15528
mRNA Refseq
Protein Refseq
Chromosome Location
12q13.1-q13.3
Function
calcidiol 1-monooxygenase activity; electron carrier activity; heme binding; iron ion binding;
Pathway
1,25-dihydroxyvitamin D3 biosynthesis, organism-specific biosystem; Biological oxidations, organism-specific biosystem; Cholecalciferol biosynthesis, organism-specific biosystem; Cholecalciferol biosynthesis, conserved biosystem; Cytochrome P450 - arranged by substrate type, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of lipids and lipoproteins, organism-specific biosystem;
MIM

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