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Panoply™ Human CREBBP Knockdown Stable Cell Line

Cat.No.
CSC-DC003626
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
CREBBP
Synonyms
CBP; RSTS; KAT3A
Gene Description
CREB binding protein (Rubinstein-Taybi syndrome)
Gene ID
UniProt ID
Q4LE28
mRNA Refseq
Protein Refseq
Chromosome Location
16p13.3
Function
MRF binding; RNA polymerase II activating transcription factor binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; RNA polymerase II transcription coactivator activity; RNA polymerase II transcription factor binding; RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription; acetyltransferase activity; core promoter proximal region sequence-specific DNA binding; histone acetyltransferase activity; p53 binding; protein binding; sequence-specific DNA binding transcription factor activity; signal transducer activity; transcription coactivator activity; contributes_to transcription coactivator activity; transcription coactivator activity; transcription factor binding; zinc ion binding;
Pathway
Activation of Gene Expression by SREBP (SREBF), organism-specific biosystem; Adherens junction, organism-specific biosystem; Adherens junction, conserved biosystem; Androgen Receptor Signaling Pathway, organism-specific biosystem; Angiogenesis, organism-specific biosystem; BMAL1:CLOCK/NPAS2 Activates Circadian Expression, organism-specific biosystem; C-MYB transcription factor network, organism-specific biosystem;
MIM

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