Panoply™ Human COL4A3 Knockdown Stable Cell Line

Name: Panoply™ Human COL4A3 Knockdown Stable Cell Line
SKU: CSC-DC003456
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC003456

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC003456
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	COL4A3
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) [ Homo sapiens ]
Gene Symbol	COL4A3
GeneID	1285
Uni ProtID	Q01955
mRNA Refseq	NM_000091.4
Protein Refseq	NP_000082.2
Chromosome Location	2q36-q37
Function	extracellular matrix structural constituent; integrin binding; integrin binding; metalloendopeptidase inhibitor activity; protein binding; structural molecule activity;
Pathway	Axon guidance, organism-specific biosystem; Collagen biosynthesis and modifying enzymes, organism-specific biosystem; Collagen formation, organism-specific biosystem; Developmental Biology, organism-specific biosystem; Extracellular matrix organization, organism-specific biosystem; Integrin cell surface interactions, organism-specific biosystem; Integrins in angiogenesis, organism-specific biosystem;
MIM	120070

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