Panoply™ Human COL18A1 Knockdown Stable Cell Line

Name: Panoply™ Human COL18A1 Knockdown Stable Cell Line
SKU: CSC-DC003441
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC003441

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC003441
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	COL18A1
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	COL18A1 collagen, type XVIII, alpha 1 [ Homo sapiens ]
Gene Symbol	COL18A1
Synonyms	KS; KNO; KNO1
Gene Description	collagen, type XVIII, alpha 1
GeneID	80781
Uni ProtID	D3DSM4
mRNA Refseq	NM_130445.2
Protein Refseq	NP_569712.2
Chromosome Location	21q22.3
Function	metal ion binding; protein binding; structural molecule activity;
Pathway	Activation of Matrix Metalloproteinases, organism-specific biosystem; Collagen biosynthesis and modifying enzymes, organism-specific biosystem; Collagen formation, organism-specific biosystem; Degradation of the extracellular matrix, organism-specific biosystem; Direct p53 effectors, organism-specific biosystem; Extracellular matrix organization, organism-specific biosystem; FOXA1 transcription factor network, organism-specific biosystem;
MIM	120328

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