Panoply™ Human CCR7 Knockdown Stable Cell Line

Name: Panoply™ Human CCR7 Knockdown Stable Cell Line
SKU: CSC-DC002677
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC002677

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC002677
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	CCR7
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	CCR7 chemokine (C-C motif) receptor 7 [ Homo sapiens ]
Gene Symbol	CCR7
Synonyms	BLR2; EBI1; CD197; CDw197; CMKBR7
Gene ID	1236
Uni Prot ID	A0N0Q0
m RNA Refseq	NM_001838.3
Protein Refseq	NP_001829.1
Chromosome Location	17q12-q21.2
Function	C-C chemokine receptor activity; C-C motif chemokine 19 receptor activity; C-C motif chemokine 21 receptor activity; G-protein coupled receptor activity; chemokine (C-C motif) ligand 19 binding; chemokine (C-C motif) ligand 21 binding;
Pathway	Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; G alpha (i) signalling events, organism-specific biosystem;
MIM	600242

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