Panoply™ Human CARD11 Knockdown Stable Cell Line

Name: Panoply™ Human CARD11 Knockdown Stable Cell Line
SKU: CSC-DC002366
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC002366

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC002366
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	CARD11
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	CARD11 caspase recruitment domain family, member 11 [ Homo sapiens ]
Gene Symbol	CARD11
Synonyms	CARD11; caspase recruitment domain family, member 11; caspase recruitment domain-containing protein 11; bcl10 interacting maguk protein 3; BIMP3; card maguk protein 1; CARMA1; carma 1; card-maguk protein 1; CARD-containing MAGUK protein 1; bcl10-interacting maguk protein 3; MGC133069;
GeneID	84433
Uni ProtID	Q9BXL7
mRNA Refseq	BC111719
Chromosome Location	7p22
Function	CARD domain binding; guanylate kinase activity; protein binding;
Pathway	Activation of NF-kappaB in B Cells, organism-specific biosystem; Adaptive Immune System, organism-specific biosystem; B Cell Receptor Signaling Pathway, organism-specific biosystem; B cell receptor signaling pathway, organism-specific biosystem; B cell receptor signaling pathway, conserved biosystem; BCR signaling pathway, organism-specific biosystem; Downstream Signaling Events Of B Cell Receptor (BCR), organism-specific biosystem;
MIM	607210

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