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CARD11


Official Full Name
caspase recruitment domain family member 11
Organism
Homo sapiens
Gene ID
84433
Background
The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10. [provided by RefSeq, Jul 2008]
Synonyms
PPBL; BENTA; BIMP3; IMD11; CARMA1; IMD11A

Cat.No. Product Name Price
SHH254685 shRNA set against Mouse CARD11 (NM_175362.2) Inquiry
SHG141009 shRNA set against Mouse Card11(NM_175362.2) Inquiry
SHH254681 shRNA set against Human CARD11 (NM_032415.4) Inquiry
SHW000254 shRNA set against Chicken CARD11 (NM_001006161) Inquiry
Cat.No. Product Name Price
CDCR041434 Human CARD11 ORF clone (NM_032415.4) Inquiry
MiUTR1M-02524 CARD11 miRNA 3'UTR clone Inquiry
MiUTR3H-09048 CARD11 miRNA 3'UTR clone Inquiry
CDCB161729 Chicken CARD11 ORF Clone (NM_001006161) Inquiry
CDCB185443 Rabbit CARD11 ORF clone (XM_008251213.1) Inquiry
CDCR041440 Mouse Card11 ORF clone (NM_175362.2) Inquiry
CDCS416275 Human CARD11 ORF Clone (BC111719) Inquiry
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