Panoply™ Human BARD1 Knockdown Stable Cell Line

Name: Panoply™ Human BARD1 Knockdown Stable Cell Line
SKU: CSC-DC001323
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC001323

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC001323
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	BARD1
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	BARD1 BRCA1 associated RING domain 1 [ Homo sapiens ]
Gene Symbol	BARD1
Gene Description	BRCA1 associated RING domain 1
Gene ID	580
Uni Prot ID	A0AVN2
m RNA Refseq	NM_000465.2
Protein Refseq	NP_000456.2
Chromosome Location	2q34-q35
Function	RNA binding; kinase binding; protein binding; protein heterodimerization activity; protein homodimerization activity; contributes_to ubiquitin-protein ligase activity; ubiquitin-protein ligase activity; zinc ion binding;
Pathway	BARD1 signaling events, organism-specific biosystem; Integrated Breast Cancer Pathway, organism-specific biosystem; Integrated Cancer pathway, organism-specific biosystem;
MIM	601593

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