Panoply™ Human ASNS Knockdown Stable Cell Line

Name: Panoply™ Human ASNS Knockdown Stable Cell Line
SKU: CSC-DC001050
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC001050

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC001050
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	ASNS
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	ASNS asparagine synthetase (glutamine-hydrolyzing) [ Homo sapiens ]
Gene Symbol	ASNS
Synonyms	ASNS; asparagine synthetase (glutamine-hydrolyzing); asparagine synthetase; asparagine synthetase [glutamine-hydrolyzing]; TS11 cell cycle control protein; glutamine-dependent asparagine synthetase; TS11;
Gene ID	440
Uni Prot ID	P08243
m RNA Refseq	BC014621
Chromosome Location	7q21-q31
Function	ATP binding; asparagine synthase (glutamine-hydrolyzing) activity; asparagine synthase (glutamine-hydrolyzing) activity; cofactor binding; ligase activity; nucleotide binding; protein homodimerization activity;
Pathway	Activation of Genes by ATF4, organism-specific biosystem; Alanine, aspartate and glutamate metabolism, organism-specific biosystem; Alanine, aspartate and glutamate metabolism, conserved biosystem; Amino acid synthesis and interconversion (transamination), organism-specific biosystem; Diabetes pathways, organism-specific biosystem; Disease, organism-specific biosystem; Metabolic pathways, organism-specific biosystem;
MIM	108370

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