Panoply™ Human APOBEC3G Knockdown Stable Cell Line

Name: Panoply™ Human APOBEC3G Knockdown Stable Cell Line
SKU: CSC-DC000779
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC000779

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC000779
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	APOBEC3G
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G [ Homo sapiens ]
Gene Symbol	APOBEC3G
Synonyms	APOBEC3G; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G; DNA dC->dU-editing enzyme APOBEC-3G; bK150C2.7; CEM15; dJ494G10.1; FLJ12740; MDS019; DNA dC-> dU-editing enzyme APOBEC-3G; APOBEC-related protein 9; dU editing enzyme; phorbolin-like protein MDS019; APOBEC-related cytidine deaminase; apolipoprotein B mRNA editing enzyme cytidine deaminase; ARCD; ARP9; ARP-9; CEM-15;
Gene ID	60489
Uni Prot ID	Q9HC16
m RNA Refseq	BC061914
Chromosome Location	22q13.1-q13.2
Function	RNA binding; cytidine deaminase activity; hydrolase activity; metal ion binding; protein homodimerization activity; zinc ion binding;
Pathway	APOBEC3G mediated resistance to HIV-1 infection, organism-specific biosystem; Disease, organism-specific biosystem; HIV Infection, organism-specific biosystem; Host Interactions of HIV factors, organism-specific biosystem; Vif-mediated degradation of APOBEC3G, organism-specific biosystem;
MIM	607113

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