Panoply™ Human ANK1 Knockdown Stable Cell Line

Name: Panoply™ Human ANK1 Knockdown Stable Cell Line
SKU: CSC-DC000600
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC000600

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC000600
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	ANK1
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	ANK1 ankyrin 1, erythrocytic [ Homo sapiens ]
Gene Symbol	ANK1
Synonyms	ANK; SPH1; SPH2
Gene Description	ankyrin 1, erythrocytic
Gene ID	286
Uni Prot ID	P16157
m RNA Refseq	NM_020475.2
Protein Refseq	NP_065208.2
Chromosome Location	8p11.1
Function	ATPase binding; cytoskeletal adaptor activity; cytoskeletal adaptor activity; enzyme binding; enzyme binding; protein binding; spectrin binding; spectrin binding; spectrin binding; structural constituent of cytoskeleton; structural molecule activity;
Pathway	Axon guidance, organism-specific biosystem; CHL1 interactions, organism-specific biosystem; Developmental Biology, organism-specific biosystem; Interaction between L1 and Ankyrins, organism-specific biosystem; L1CAM interactions, organism-specific biosystem; Neurofascin interactions, organism-specific biosystem; NrCAM interactions, organism-specific biosystem;
MIM	612641

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