Panoply™ Human ALDH18A1 Knockdown Stable Cell Line

Name: Panoply™ Human ALDH18A1 Knockdown Stable Cell Line
SKU: CSC-DC000475
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC000475

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC000475
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	ALDH18A1
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	ALDH18A1 aldehyde dehydrogenase 18 family, member A1 [ Homo sapiens ]
Gene Symbol	ALDH18A1
Synonyms	GSAS; P5CS; PYCS; ARCL3A
Gene Description	aldehyde dehydrogenase 18 family, member A1
Gene ID	5832
Uni Prot ID	P54886
m RNA Refseq	NM_001017423.1
Protein Refseq	NP_001017423.1
Chromosome Location	10q24.3
Function	ATP binding; glutamate 5-kinase activity; glutamate-5-semialdehyde dehydrogenase activity;
Pathway	Amino acid synthesis and interconversion (transamination), organism-specific biosystem; Arginine and proline metabolism, organism-specific biosystem; Arginine and proline metabolism, conserved biosystem; Metabolism, organism-specific biosystem; Metabolism of amino acids and derivatives, organism-specific biosystem; Ornithine biosynthesis, glutamate => ornithine, without N-acetylation, organism-specific biosystem;
MIM	138250

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