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ALDH18A1


Official Full Name
aldehyde dehydrogenase 18 family member A1
Organism
Homo sapiens
Gene ID
5832
Background
This gene is a member of the aldehyde dehydrogenase family and encodes a bifunctional ATP- and NADPH-dependent mitochondrial enzyme with both gamma-glutamyl kinase and gamma-glutamyl phosphate reductase activities. The encoded protein catalyzes the reduction of glutamate to delta1-pyrroline-5-carboxylate, a critical step in the de novo biosynthesis of proline, ornithine and arginine. Mutations in this gene lead to hyperammonemia, hypoornithinemia, hypocitrullinemia, hypoargininemia and hypoprolinemia and may be associated with neurodegeneration, cataracts and connective tissue diseases. Alternatively spliced transcript variants, encoding different isoforms, have been described for this gene. [provided by RefSeq, Jul 2008]
Synonyms
GSAS; P5CS; PYCS; SPG9; ADCL3; SPG9A; SPG9B; ARCL3A

Cat.No. Product Name Price
SHH234782 shRNA set against Mouse ALDH18A1 (NM_019698.2) Inquiry
SHG052129 shRNA set against Human ALDH18A1(NM_001017423.1) Inquiry
SHG052189 shRNA set against Human ALDH18A1(NM_002860.3) Inquiry
SHH234786 shRNA set against Rat ALDH18A1 (NM_001108524.1) Inquiry
SHW011291 shRNA set against Danio rerio ALDH18A1 (NM_001083546) Inquiry
Cat.No. Product Name Price
CDCB172766 Danio rerio ALDH18A1 ORF Clone (NM_001083546) Inquiry
CDCR270494 Mouse Aldh18a1 ORF Clone(NM_153554.2) Inquiry
CDCS406591 Human ALDH18A1 ORF Clone (BC117240) Inquiry
CDFH000615 Human ALDH18A1 cDNA Clone(NM_001017423.1) Inquiry
CDFH000616 Human ALDH18A1 cDNA Clone(NM_002860.3) Inquiry
CDFH000617 Human ALDH18A1 cDNA Clone(NM_002860.3) Inquiry
CDFR008136 Rat Aldh18a1 cDNA Clone(NM_001108524.1) Inquiry
MiUTR1H-00284 ALDH18A1 miRNA 3'UTR clone Inquiry
MiUTR1H-00285 ALDH18A1 miRNA 3'UTR clone Inquiry
SKO0299 ALDH18A1 Validated sgRNA vector Inquiry
CDCB186369 Rabbit ALDH18A1 ORF clone (XM_002718544.2) Inquiry
CDCR026546 Human ALDH18A1 ORF clone (NM_001017423.1) Inquiry
CDCR026548 Human ALDH18A1 ORF clone (NM_002860.3) Inquiry
CDCR254201 Mouse Aldh18a1 ORF Clone(NM_019698.2) Inquiry
CDCR375017 Rat Aldh18a1 ORF Clone(NM_001108524.1) Inquiry
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