Panoply™ Human ALAD Knockdown Stable Cell Line

Name: Panoply™ Human ALAD Knockdown Stable Cell Line
SKU: CSC-DC000469
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC000469

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

Safety and Packaging

Gene Information

Cat. No.	CSC-DC000469
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	ALAD
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	ALAD aminolevulinate dehydratase [ Homo sapiens ]
Gene Symbol	ALAD
Synonyms	PBGS; ALADH
Gene ID	210
Uni Prot ID	P13716
m RNA Refseq	NM_000031.5
Protein Refseq	NP_000022.3
Chromosome Location	9q33.1
Function	catalytic activity; identical protein binding; lead ion binding; porphobilinogen synthase activity; porphobilinogen synthase activity; zinc ion binding;
Pathway	Heme Biosynthesis, organism-specific biosystem; Heme biosynthesis, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of porphyrins, organism-specific biosystem; Porphyrin and chlorophyll metabolism, organism-specific biosystem; Porphyrin and chlorophyll metabolism, conserved biosystem; heme biosynthesis II, organism-specific biosystem;
MIM	125270

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