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Panoply™ Human ACO1 Knockdown Stable Cell Line

Cat.No.
CSC-DC000139
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
ACO1
Synonyms
IRP1; ACONS; IREB1; IREBP; IREBP1
Gene Description
aconitase 1, soluble
Gene ID
UniProt ID
P21399
mRNA Refseq
Protein Refseq
Chromosome Location
9p21.1
Function
4 iron, 4 sulfur cluster binding; RNA binding; RNA binding; aconitate hydratase activity; citrate hydro-lyase (cis-aconitate-forming) activity; iron-responsive element binding; isocitrate hydro-lyase (cis-aconitate-forming) activity; mRNA 5-UTR binding; metal ion binding; protein binding;
Pathway
Citrate cycle (TCA cycle), organism-specific biosystem; Citrate cycle (TCA cycle), conserved biosystem; Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate, organism-specific biosystem; Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate, conserved biosystem; Glyoxylate and dicarboxylate metabolism, organism-specific biosystem;
MIM

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